Cannabis Hyperemesis Syndrome in Adolescents and Young Adults

Posted on January 06, 2026

In this presentation, Laura Grubb, MD, MPH, discusses how cannabis use has increased substantially among adolescents and young adults, paralleled by a rising incidence of Cannabis Hyperemesis Syndrome (CHS)—a frequently under-recognized cause of recurrent, severe nausea and vomiting. CHS is often misdiagnosed, leading to repeated emergency department visits, extensive diagnostic testing, delayed recognition of the role of cannabis use, and prolonged morbidity. This activity provides a clinically practical, evidence-based review of CHS in adolescents and young adults. Using real-world case examples, participants will review the physiology of vomiting, distinguish CHS from other causes of recurrent vomiting, and apply validated diagnostic criteria. The course emphasizes high-yield clinical features, including compulsive hot bathing, and outlines evidence-based acute management strategies. Particular attention is given to the challenges of treating cannabis use disorder in adolescents and young adults, including ambivalence about cessation, high relapse rates, limited pharmacologic options, and the need for repeated, longitudinal counseling. This activity is designed for clinicians caring for adolescents and young adults in primary care, emergency, gastroenterology, and behavioral health settings.

For more information and to register visit: https://mesudlearningcommunity.org/events/cannabis-hyperemesis-syndrome-in-adolescents-and-young-adults/

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